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The biology behind behavioural changes in frontotemporal dementia

What is the molecular basis for the abnormal behaviour seen in FTD? Scientists of the University of Massachusetts Medical School in Worcester have found a biological explanation for the behavioural changes that some people with frontotemporal dementia experience. The team from the University of Massachusetts did this by studying the behaviour of mice with a […]

C9ORF72

C9ORF72 – how do problems in this gene cause FTD and motor neurone disease?

Recent studies have shown that mutations in a gene called C9orf72 are a major cause of not only FTD but also motor neurone disease. Researchers are now trying to work out exactly what the mechanisms are that lead to disease. In 2011 two research groups independently discovered a mutation in a gene called C9ORF72 as […]