We’re excited to share that we’ve recently introduced a portable MRI scanner, called a Hyperfine, into our research!
Unlike traditional MRI machines, which are large, fixed installations in hospitals, a portable MRI, sometimes referred to as a field scanner, is much smaller and can be moved between locations. It is easily operated by a tablet with minimal technical training. It is potentially safe for people with metal implants or devices. In addition, only the head needs to be placed inside the scanner, rather than the entire body, which means people may find it more comfortable to undergo a scan.
This flexibility means that the scanner is cheaper to run and operate, and that more participants may be able to have scans. It also opens up the possibility of carrying out scans outside of major hospitals, reducing the need for long-distance travel to specialized research centers. One day, we hope this could allow participants to undergo scans at local facilities equipped with portable MRI machines.

Left: Traditional MRI Scanner
Right: Portable MRI Scanner
This idea forms the focus of Erin’s PhD research, where she is studying how well scans from the portable Hyperfine scanner compare to those from our traditional MRI machines. Her work is part of the Genetic Frontotemporal Dementia Initiative (GENFI), which aims to identify the earliest brain changes in familial FTD. By recognizing these early signs, we can better understand how they might be used in clinical trials to determine whether a treatment is effective. If portable MRI scans prove to be comparable to traditional ones, it could make screening for FTD in both clinical and research settings faster, more comfortable, and more widely accessible!
So, how does the portable scanner actually work?
This week, Erin and Eva carried out a test run. Eva described the experience as much more comfortable and quicker than a traditional MRI: She only needed to lie down with her head inside the scanner, an arrangement that Eva found less claustrophobic and noticeably quieter than conventional machines. Another advantage: the scanner can even be operated via an iPad, making it simple and flexible to use.
We’re hopeful that integrating portable MRI technology into our research will increase accessibility, not just for familial FTD, but for other conditions as well. We’re excited to see the results of Erin’s analysis as we begin scanning our first participants!

If you are interested in learning more about the portable MRI scanner and Erin’s work, please click here.
Amelia Blesius, on behalf of the FTD talk team.
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