Aitana is the senior research fellow in the team. She is a Race Against Dementia ARUK fellow funded until the end of 2026. She has a BSc in Biology from the University of Alicante and a MSc and PhD in Neuroscience from the Universidad Miguel Hernandez de Elche at Instituto de Neurociencias de Alicante. Her PhD investigated novel biomarkers for Alzheimer’s Disease during which time she spent 3 months at the University of Gothenburg in Sweden learning about the development of ELISAs. After completing her PhD, she moved to London and started her first postdoc at the UK Dementia Research Institute where her main project was to develop fluid biomarkers of microglial activation. She now works in the Biomarker Lab at the UK DRI helping to develop novel biomarkers for FTD and with a focus on assessing synaptic dysfunction. Her fellowship work focuses on blood biomarkers through the study of exosomes.
- ISFTD Early and Mid Career Online Symposium 2023 (virtual, November 2023): Targeted proteomic search reveals new actors in the synaptic and lysosomal dysfunction in genetic FTD, a GENFI study
- UK DRI Proteomics Symposium (Edinburgh, October 2023): How am I using proteomics to find biomarkers for frontotemporal dementia?
- AAIC 2023, ISTAART FTD-PIA Day (Amsterdam, July 2023): Tandem Mass Tag-based proteomics in the GENFI cohort: the specific and shared signatures in genetic frontotemporal dementia
- For Women in STEM Workshop (Amsterdam, July 2023): A new horizon for fluid biomarkers in genetic frontotemporal dementia: an unbiased proteomics study
- GENFI Investigators Meeting (Brescia, June 2023): An update on TMT proteomics in the GENFI cohort
- UK DRI Early Career Researchers Symposium, Synapse Theme (London, June 2023): Fluid biomarkers of synaptic dysfunction in FTD
- FTD-UK 2023 (London, May 2023): Synaptic biomarkers in frontotemporal dementia
- AD/PD International Conference 2023 (Gothenburg, March 2023): A new horizon for fluid biomarkers in genetic frontotemporal dementia: an unbiased proteomics study. Junior Faculty Award
- ARUK Research Conference 2023 (Aberdeen, March 2023): Untargeted proteomics in the GENFI cohort: the discovery of novel biomarkers for genetic frontotemporal dementia
- Lunch and Learn with ARUK (virtual, February 2023)
- DEMON Network, Biomarkers Working Group Seminar (virtual, January 2023): Current state of fluid biomarkers in frontotemporal dementia: can we see a clear picture?
- INA Christmas Meeting (Alicante, December 2022): Racing against frontotemporal dementia: a new horizon of fluid biomarkers for diagnosis and treatment
- Making it Brain, UK DRI Conference for Undergraduate Students (virtual, September 2022): What can blood tell us about dementia? Tools to explore the brain from the outside
- ARUK Research Conference 2022 (Brighton, March 2022): Exploring the utility of synaptic markers in frontotemporal dementia
- AAIC 2021, Focused Research Session (virtual, July 2021): Differential synaptic marker involvement in the different genetic forms of frontotemporal dementia
- AAIC 2020, FTD-PIA Day (virtual, July 2020): Lipid mediators in frontotemporal dementia – novel insights into neuroinflammation
- AAIC 2023 (Amsterdam, July 2023): Targeted proteomic search reveals new actors in the synaptic and lysosomal dysfunction in genetic FTD, a GENFI study
- ARUK 2023 (Aberdeen, March 2023): Untargeted proteomics in the GENFI cohort: the discovery of novel biomarkers for genetic frontotemporal dementia
- ISFTD 2022 (Lille, November 2022): Profiling lipid metabolism alterations in genetic frontotemporal dementia within the GENFI cohort
- ARUK 2022 (Brighton, March 2022): Exploring the utility of synaptic markers in frontotemporal dementia
- AAIC 2021 (virtual, July 2021): Differential synaptic marker involvement in the different genetic forms of frontotemporal dementia
- Vesicle Trafficking and Pathways to Neurodegeneration 2021 (virtual, May 2021): Differential synaptic marker involvement in the different genetic forms of frontotemporal dementia – see video description here
- BNA 2021 (virtual, April 2021): Differential chemokine changes are seen in the different variants of primary progressive aphasia – see video description here
- ARUK 2021 (virtual, March 2021): Differential chemokine changes are seen in the different variants of primary progressive aphasia
- Differential patterns of lysosomal dysfunction are seen in the clinicopathological forms of primary progressive aphasia. J Neurol. 2023. doi.org/10.1007/s00415-023-12063-9.
- Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia. Sogorb-Esteve A, Nilsson J, Swift IJ, Heller C, Bocchetta M, Russell LL, Peakman G, Convery RS, van Swieten JC, Seelaar H, Borroni B, Galimberti D, Sanchez-Valle R, Laforce R Jr, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, Santana I, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Sorbi S, Le Ber I, Pasquier F, Gobom J, Brinkmalm A, Blennow K, Zetterberg H, Rohrer JD; GENetic FTD Initiative. Alzheimers Res Ther. 2022;14(1):118. doi: 10.1186/s13195-022-01042-3. PMID: 36045450; PMCID: PMC9429339.
- Differential chemokine alteration in the variants of primary progressive aphasia-a role for neuroinflammation. Sogorb-Esteve A, Swift IJ, Woollacott IOC, Warren JD, Zetterberg H, Rohrer JD. J Neuroinflammation. 2021;18(1):224. doi: 10.1186/s12974-021-02247-3. PMID: 34602080; PMCID: PMC8489077.
- Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation. Sogorb-Esteve A, Colas RA, Dalli J, Rohrer JD. J Alzheimers Dis. 2021;84(1):283-289. doi: 10.3233/JAD-210559. PMID: 34542074.
- Fluid biomarkers in frontotemporal dementia: past, present and future. Swift IJ, Sogorb-Esteve A, Heller C, Synofzik M, Otto M, Graff C, Galimberti D, Todd E, Heslegrave AJ, van der Ende EL, Van Swieten JC, Zetterberg H, Rohrer JD. J Neurol Neurosurg Psychiatry. 2021;92(2):204-215. doi: 10.1136/jnnp-2020-323520. Epub 2020 Nov 13. PMID: 33188134.
