Martina is a Lecturer in Neuroscience and an Honorary Senior Research Fellow. She has a BSc and MSc from the University of Padua in Italy and then undertook a PhD at the University of Brescia in Italy in Neuroscience. During her PhD she spent 18 months at UCL with our team working on understanding the role of the hypothalamus and the cerebellum in FTD using MR imaging. At the end of her PhD in 2015 she returned to UCL. Her research mainly focuses on the measurement of specific brain structures using MR imaging and how they are structurally and functionally connected in the different forms of FTD. Her work on the medial temporal lobe in semantic dementia was awarded the runner up prize at the 2018 ICFTD meeting, her work on thalamic subnuclei in FTD was awarded the 2019 FTD UK Early Career Researcher Clinical Science Prize, and her work applying neurite orientation dispersion and density imaging to FTD was awarded the Best Clinical Presentation during the 2023 ISFTD EMCR Symposium. Martina is a STEM Ambassador and a Fellow of the Higher Education Academy in UK.
- ISFTD Early and Mid Career Online Symposium 2023 (virtual, November): White matter microstructural changes in sporadic and genetic FTD using neurite orientation dispersion and density imaging
- SINDem Webinar Series 2023 (virtual, May): MRI in frontotemporal dementia: what have we learnt so far?
- 15th CONy – Alzheimer’s Association and CONy Joint Meeting on FTD 2021 (virtual, September): Imaging biomarkers in FTD
- AAIC 2021 (virtual, July): From brain volumes to subgroup classification in genetic mutation carriers for frontotemporal dementia: a cluster analysis in the GENFI study
- ISTAART Neuroimaging and FTD PIA Webinar 2021 (virtual, June): What have we learned from MRI in FTD in the last 10 years
- 6th FTD-UK 2019 (Cambridge, October): Thalamic nuclei in frontotemporal dementia: mediodorsal nucleus involvement is universal but pulvinar atrophy is unique to C9orf72
- 11th ISFTD 2018 (Sydney, November): Progressive medial temporal subnuclei involvement in semantic dementia
- 10th ISFTD 2016 (Munich, September): Multimodal imaging analysis of C9orf72-associated FTD in the Genetic Frontotemporal dementia Initiative (GENFI) study
- 3rd FTD-UK 2016 (Cambridge, November): Imaging of subcortical structures and their connections in FTD
- AAIC 2015 (Washington, July): Detailed structural analysis of the hypothalamus in behavioural variant frontotemporal dementia
- ARUK 2015 Conference PhD Day (London, March): Detailed structural analysis of the hypothalamus in behavioural variant frontotemporal dementia
- AAIC 2023 (Amsterdam, July): White matter microstructural changes in sporadic and genetic FTD using neurite orientation dispersion and density imaging
- 13th ISFTD 2022 (Lille, November): White matter microstructural changes in presymptomatic and symptomatic FTD using neurite orientation dispersion and density imaging
- AAIC 2021 (virtual, July): Detecting clinical progression from abnormal regional brain volumes at baseline in genetic frontotemporal dementia
- ARUK 2021 Research Conference (virtual, March): Differential early subcortical involvement in genetic frontotemporal dementia within the GENFI cohort
- 11th ISFTD 2018 (Sydney, November): Amygdalar subnuclei are particularly affected in tau-MAPT, tau-Pick’s disease and TDP-43 type C-associated frontotemporal dementia
- First International Symposium on PSP & CBD 2018 (London, October): A novel automated segmentation tool detects differential brainstem involvement in atypical parkinsonian syndromes
- AAIC 2017 (London, July): Thalamic atrophy in frontotemporal dementia: not just a C9orf72 problem
- ARUK 2016 Research Conference (Manchester, March): Multimodal structural imaging analysis of C9orf72-associated FTD
- AAIC 2015 (Washington, July): Detailed structural analysis of the hypothalamus in behavioural variant frontotemporal dementia
- AAIC 2015 (Washington, July): Volumetry of the cerebellum and its subregions in genetic frontotemporal dementia
- 9th ISFTD 2014 (Vancouver, October): Hypothalamic atrophy in behavioural variant frontotemporal dementia and its relationship to eating behaviour
- In vivo hypothalamic regional volumetry across the frontotemporal dementia spectrum. Shapiro NL, Todd EG, Billot B, Cash DM, Iglesias JE, Warren JD, Rohrer JD, Bocchetta M. NeuroImage: Clinical. 2022;35:103084
- Basal forebrain atrophy in frontotemporal dementia. Convery RS, Neason MR, Cash DM, Cardoso MJ, Modat M, Ourselin S, Warren JD, Rohrer JD, Bocchetta M. Neuroimage Clin. 2020;26:102210.
- Structural MRI predicts clinical progression in presymptomatic FTD: findings from the GENFI cohort. Bocchetta M, Todd EG, Bouzigues A, Cash DM, Nicholas J, Convery RS, Russell LL, Thomas DL, Malone IB, Iglasias JE, van Swieten JC, Jiskoot LC, Seelaar H, Borroni B, Galimberti D, Sánchez-Valle R, Laforce Jr. R, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger EC, Tagliavini F, de Mendonça A, Santana I, Butler C, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Sorbi S, Le Ber I, Pasquier F, Rohrer JD, on behalf of the Genetic Frontotemporal dementia Initiative (GENFI). Brain Communications. 2023;5(2):fcad061.
- Distinct hypothalamic involvement in the amyotrophic lateral sclerosis-frontotemporal dementia spectrum. Tse NY*, Bocchetta M* (*joint first authors), Todd EG, Devenney EM, Tu S, Caga C, Hodges JR, Halliday GM, Irish M, Kiernan MC, Piguet O, Rohrer JD, Ahmed RM. NeuroImage: Clinical. 2022;37:103281.
- Tackling clinical heterogeneity across the ALS-FTD spectrum using a transdiagnostic approach. Ahmed RM*, Bocchetta M* (*joint first authors), Todd EG, Tse NY, Devenney EM, Tu S, Caga J, Hodges JR, Halliday GM, Irish M, Kiernan MC, Piguet O, Rohrer JD. Brain Communications. 2021;3(4):fcab257. doi: 10.1093/braincomms/fcab257
- Brain Sci. 2022 Mar 1;12(3):336.
- Looking beneath the surface: the importance of subcortical structures in frontotemporal dementia. Brain Commun. 2021 Jul 16;3(3):fcab158.
- Differential early subcortical involvement in genetic FTD within the GENFI cohort. Bocchetta M, Todd E, Peakman G, Cash D, Convery R, Russell L, Thomas D, Iglesias JE, van Swieten J, Jiskoot L, Seelaar H, Borroni B, Galimberti D, Sanchez-Valle R, Laforce R, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe B, Vandenberghe R, Finger E, Tagliavini F, de Mendonca A, Santana I, Butler C, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Sorbi S, Le Ber I, Pasquier F, Rohrer JD. Neuroimage Clin. 2021;30:102646.
- In vivo staging of frontotemporal lobar degeneration TDP-43 type C pathology. Bocchetta M*, Iglesias Espinosa MDM* (*joint first authors), Lashley T, Warren JD, Rohrer JD. Alzheimers Res Ther. 2020;12(1):34.
- Thalamic nuclei in frontotemporal dementia: Mediodorsal nucleus involvement is universal but pulvinar atrophy is unique to C9orf72. Bocchetta M, Iglesias JE, Neason M, Cash DM, Warren JD, Rohrer JD. Human Brain Mapping 2020;41(4):1006-1016.
- Automated Brainstem Segmentation Detects Differential Involvement in Atypical Parkinsonian Syndromes. Bocchetta M, Iglesias JE, Chelban V, Jabbari E, Lamb R, Russell LL, Greaves CV, Neason M, Cash DM, Thomas DL, Warren JD, Woodside J, Houlden H, Morris HR, Rohrer JD. Journal of Movement Disorders. 2020;13(1):39-46.
- Segmentation of medial temporal subregions reveals early right-sided involvement in semantic variant PPA. Bocchetta M, Iglesias JE, Russell LL, Greaves CV, Marshall CR, Scelsi MA, Cash DM, Ourselin S, Warren JD, Rohrer JD. Alzheimer’s Research & Therapy. 2019;11(1):41.
- Amygdala subnuclei are differentially affected in the different genetic and pathological forms of frontotemporal dementia. Bocchetta M, Iglesias JE, Cash DM, Warren JD, Rohrer JD. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring. 2019;11:136-141.
- Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort. Sellami L*, Bocchetta M* (*joint first authors), Masellis M, Cash DM, Dick KM, van Swieten J, Borroni B, Galimberti D, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni G, Finger E, Mendonça A, Sorbi S, Warren JD, Rohrer JD, Laforce Jr R, on behalf of the Genetic FTD Initiative. J Alzheimers Dis. 2018;65(1):147-163.
- Hippocampal Subfield Volumetry: Differential Pattern of Atrophy in Different Forms of Genetic Frontotemporal Dementia. Bocchetta M, Iglesias JE, Scelsi MA, Cash DM, Cardoso MJ, Modat M, Altmann A, Ourselin S, Warren JD, Rohrer JD. Journal of Alzheimer’s Disease. 2018;64(2):497-504.
- Thalamic atrophy in frontotemporal dementia – Not just a C9orf72 problem. Bocchetta M, Gordon E, Cardoso MJ, Modat M, Ourselin S, Warren JD, Rohrer JD. NeuroImage Clin. 2018;18:675-681.
- Patterns of regional cerebellar atrophy in genetic frontotemporal dementia. Bocchetta M, Cardoso MJ, Cash DM, Ourselin S, Warren JD, Rohrer JD. Neuroimage Clin. 2016;11:287-90.
- The habenula: an under-recognised area of importance in frontotemporal dementia? Bocchetta M, Gordon E, Marshall CR, Slattery CF, Cardoso MJ, Cash DM, Espak M, Modat M, Ourselin S, Frisoni GB, Schott JM, Warren JD, Rohrer JD. J Neurol Neurosurg Psychiatry. 2016;87(8):910-2.
- Detailed volumetric analysis of the hypothalamus in behavioral variant frontotemporal dementia. Bocchetta M, Gordon E, Manning E, Barnes J, Cash DM, Espak M, Thomas DL, Modat M, Rossor MN, Warren JD, Ourselin S, Frisoni GB, Rohrer JD. J Neurol. 2015;262(12):2635-42.
